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NOVEL CLINICAL/TRANSLATIONAL METHODS CATALYST AWARDS Project Award Amount $30,000 Description of Grant AreaThese grants will be used to support planning activities or pilot studies leading to the development or validation of novel methodologies for performing or supporting clinical or translational research. Appropriate topics might include, for example, new translational methodologies (e.g., for monitoring disease progression or drug response), developing new phenotyping methods that are more objective and quantifiable, the development of biomarkers for research purposes, research into clinical trial designs, clinical informatics for longitudinal studies, home-based research devices and methods, predictive toxicology or pharmacogenomics for use in clinical trials, and methods for evaluating the impact of clinical and translational studies. These grants are distinct from Translational Technology Awards in including non-technological methods and in not requiring that the new methods be made available to the UCSF community as a core function. Traditional sources of major funding for development of novel methodologies are limited, particularly for the most innovative methods at their nascence. Funding from NIH is generally based on testing specific hypotheses, and justifying methodological research with hypothesis testing may be awkward and contrived, particularly when the methods are being developed independent of a specific application. Peer review may be particularly unkind to approaches that are very innovative and not previously validated. The SOS Center, working with other CTSI programs, will provide funds for pilot and planning grants designed to lead to further funding and development of novel clinical/translational methods. Each funded grant will have a maximum budget of $30,000 and may be used for partial investigator salary support. Projects are for one year and are not renewable. A progress report is expected at the end of and one year following the funding period, identifying resulting publications and subsequent applications and funding to support the expanded/extended projects. Any resulting publication must directly cite CTSI SOS Center funding. The proposed research must be clearly justified as being on the path to potential benefit to humans. Note: As a general rule, within any category, priority is given to applicants who have never received funding in that category, except for the Fogarty International Training Awards in HIV/AIDS and International Mentored Scientist Award Program in HIV/AIDS. Eligibility Criteria for Evaluation of Applications Note: Clinical and translational research includes bench to bedside/laboratory to human (T1) translational research, clinical research, and bedside to the community/evidence to practice (T2) research. Contact: |
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