Weill Pilot Award for Junior Investigators in the Neurosciences

Project Award Amount $40,000

Description

The UCSF Weill Institute for Neurosciences, established by the extraordinary generosity of Joan and Sanford I. Weill, brings together world-class researchers with top-ranked physicians to solve some of the most complex challenges in the human brain.

The Weill Institute’s 2019 RAP Awards seek to fuel innovation in neuroscience by fostering high need, high reward, clinical/translational research through funding of highly meritorious research projects and supporting high-potential neuroscience researchers.

The target for this program is to support junior investigators working on a broad spectrum of neuroscience challenges, including therapeutics, diagnostics, imaging technology, biomarker discovery/validation, and computational methods. We seek to support creative research projects that are focused on improved patient outcomes, especially those that employ concepts of convergent neuroscience research, crossing levels of analysis from genomics and imaging to behavior and implementation, and considering the dimension of time.

Each pilot project will have a maximum budget of $40,000. Pilot projects are for one year and are not renewable. A progress report is required at the end of the funding period, identifying resulting publications and subsequent funding obtained to support the expanded/extended projects. Any resulting publication must directly acknowledge the funding agency.

Eligibility

Eligibility requirements need to be met as of date of submission, no waivers will be accepted.

Who's Eligible:

UCSF Faculty in any series (Ladder Rank, In Residence, Clinical X, Health Science Clinical, Adjunct) in the ranks of Instructors and Assistant Professors may apply. Fellows, Postdocs and appointees to the Professional Research Series may also apply.

Who's Not Eligible:

Associate and Full Professors; Residents, Specialists and appointees to the Librarian Series.

Submission Rules

Criteria for Review/Evaluation of Applications

  • Projects should address problems with high impact to human health;
  • Projects should employ an innovative neuroscience approach;
  • Projects should lead to and describe tangible benefit to patients, including the likelihood that follow-up studies will have an immediate impact;
  • Projects should employ convergent neuroscience concepts; bridging different disciplines of enquiry is encouraged;
  • Projects that address the challenges of interoperability, health disparities, privacy, participant engagement, consent, security, ethical and/or regulatory issues, are also encouraged;
  • Where applicable, projects should describe the potential downstream use of tools, measurements, approaches, and data, including open public accessibility of generated data and publications;
  • Projects that leverage the electronic health record data from across the UC Health centers are encouraged.

Pilot projects that involve human subjects will require human research committee approval before funding is released.

Selection of Awardees

Funding decisions are made independently by each funding agency based on several factors – scientific review score, alignment of proposal to funder’s strategic goals, proposal research area of focus, and specifically called out eligibility or other requirements like membership in a center, affiliation with a specific school or relevance to a stated auxiliary topic.

TO APPLY:

STEP 1) Complete the electronic application form
STEP 2) Upload your proposal as a SINGLE PDF that includes all the things listed in numeric order in the instructions below.


INSTRUCTIONS FOR PROPOSAL PDF

Please write your proposal following the instructions listed below and create one single PDF file. Do not include form fields in your PDF document.

Proposal Length: Maximum 6 pages, including figures and tables, excluding table of contents and literature cited, community engagement component, if applicable.
Format Requirements: Arial font; 11 pt; minimum 0.5 inch for all margins; no appendices; include page numbers and table of contents.

Resubmissions
Definition: Same research topic with an amended application or research plan rather than a new research topic and new research plan.
Requirements: Please use up to one extra page to introduce your revised proposal, addressing the issues raised in the review, and any additional changes to your proposal. A new letter from the Chair is not required if the resubmission is within 2 cycles (one skipped cycle max). You will include the old letter and state your resubmission is within 2 cycles and new letter is not required. Make sure the new changes are highlighted in bold or italic font so the reviewers can easily see where and how the proposal has changed. Do not use track changes.

1. P.I. Name(s) - Optionally, you may apply with two PIs. If funded, PI1 will be the primary contact for the award set up and management. If the proposal has multiple PIs, both PI1 and PI2 need to meet the eligibility criteria listed for this grant mechanism. Only ONE application as PI (PI1 or PI2) is permitted per cycle.

2. Project Title

3. Proposal (maximum 6 pages, including figures and tables, excluding literature cited and community engagement component (if applicable)).

  • Aims. Do not submit an application that describes an idea that is the same or similar to one used in a previously funded RAP grant. If it is a similar idea, describe how the new proposed research is uniquely different.
  • Feasibility: Describe what steps you are taking to ensure the proposed project can be completed within the one year project period for this grant (approximately 300 word max).
  • Background and Significance
  • Preliminary studies
  • Experimental Design and Methods (include time-table)
  • Explain how this pilot project is important for your career goals (e.g., lead to major funding, etc.)
  • Mentoring Plan: (required for fellows and junior faculty)
    Please describe the plan for oversight of this project by your mentor(s), including the specific role of your primary mentor named in this application.
  • Community Engagement Component (optional) describe a community engagement component for your research proposal (300 words max). Projects that engage in community partnership practices are characterized by increasing level of community involvement, impact, trust and communication flow (from stages of involve, collaborate and shared leadership). For examples of excellence in community partnerships, please visit: https://partnerships.ucsf.edu/excellence-partnership-awardees#2014. Community broadly includes local, state, national and international stakeholders. Stakeholders include researchers, health systems, government, policy makers, community based organizations, community residents and patients. For clarification, questions and consultations, please contact either [email protected] or [email protected]
  • Literature cited (not included in page limit)

4. Detailed Budget $40,000 maximum per proposal and please round up to the nearest thousand (i.e. instead of $39,869 list $40,000).
Use the following form: PHS 398 Form Page 4, "Detailed Budget for the Initial Period": http://grants.nih.gov/grants/funding/phs398/phs398.html
Add the network recharge rates to your budget.

 

Allowable

Not Allowable

PI Salary *

X

 

Co-Investigator(s) Salary

X

 

Post Doc Salary

X

 

Administrative Support

 

X

Supplies

X

 

Equipment

X

 

Software

X

 

Personal Computers

 

X

Mailing

 

X

Tuition

 

X

Travel

X

 

Research Staff Support (e.g. SRA; Lab. Technician)

X

 

Patient Care

 

X

International Subcontracts

 

X

Indirect costs on subcontracts

 

X

*NIH base salary cap. Fully justify all requests. Generally PI partial salary support should not exceed 10% of the award budget - NOT % of PI salary. An amount over 10% of the award budget must be well justified. Multiple PIs can decide how to distribute that 10% salary support among themselves (e.g., 5%/5% or 6%/4%).

5. Budget Justification: Clearly and fully justify all costs.

6. NIH Bio-sketch of Principal Investigator(s) and Co-Investigator(s) and UCSF Faculty Mentor(s) (if applicable) (6 page maximum):
Use this version: Biosketch Version E. Include biosketches for all PIs of a multi-PI application, and any other key personnel such as Co-Investigator(s) or UCSF Faculty Mentor(s). In section "D. Additional Information", list the relevant recent past, planned, active, and pending proposals, including percent effort and total direct costs (annual), where possible. Include a brief discussion of any potential overlap with the current proposal.

7. Letter(s) of support: Provide a letter of support from the department chair or other unit head. In addition, for junior investigators, department chairs/unit heads should comment on the independence of the applicant and availability of research space and other resources for the proposed research. Include the letter of support at the end of your PDF proposal and address it to the RAP Committee. If there are multiple (two) PIs, a letter of support is required for both PIs. If PIs are in the same department, the chair can vouch for both PIs in a single letter.