Gilead HIV Cure Mentored Scientist Award

Project Award Amount $45,000

Description

The purpose of the Gilead HIV Cure Mentored Scientist Award at the amfAR Institute for HIV Cure Research is to mentor and train early stage investigators participating in HIV cure research. The award is open to investigators at a senior stage of clinical or postdoctoral training, and to new faculty at UCSF and affiliated partner institutes. Cure research projects can be in clinical or basic laboratory science and must contribute to the goals of the amfAR Institute for HIV Cure Research. Applicants for this award must indicate a faculty research mentor(s) who will commit to guiding the applicant throughout the duration of the proposed project.

The award level for this program is $45,000 in direct costs for one year. Any carry forward of funding will require pre-approval and must be fully justified. Progress reports will be due at six months and at the end of the project period. Funding is available for four awards.

Eligibility

NOTE: Eligibility requirements need to be met as of date of submission; no waivers are allowed.

Who’s Eligible:

  • Postdoctoral or clinical fellows in training.
  • Current faculty in all series – including adjunct and professional research series - at the assistant professor or clinical instructor level (including acting positions) who have not yet received an R01-equivalent award in HIV/AIDS.
  • Investigators must be at UCSF or an affiliated partner institute

Designation of a Research Mentor:

All mentored award applications require a faculty research mentor. The mentor’s role is to provide oversight on the planning, direction, and execution of the proposed research. The mentor should be recognized as an accomplished investigator in HIV cure research, and should be able to demonstrate past success in training/mentoring independent investigators. In addition, the mentor must commit to mentoring the applicant throughout the duration of the research project. The research mentor must support, advise, and guide the research portion of your application before submitting it to RAP.

Criteria for Review/Evaluation of Applications:

Projects will be evaluated based on the quality of the proposed scientific investigation, the significance of the proposed scientific investigation, and the quality and potential of the applicant and the research team.


CHR/IRB Approvals - All research requires IRB approval and human subjects training certification. All awardees whose research involves human subjects (e.g., patients or cohorts or the use of specimens/samples/medical record data) will be required to apply for and obtain approval for their research from the UCSF Committee on Human Research (CHR). At no point during the project can CHR or IRB approval expire. Should IRB approval expire before the study is complete, all study research must cease immediately until approval has been obtained.

Note: Funding for research projects involving human subjects will not be released until a CHR approval or CHR waiver letter (citing the awardee's name) and proof of human subjects training have been received. If you have any questions regarding the CHR approval process, please contact the MSO for your department. New investigators should visit the UCSF CHR website for details on when and how to apply for CHR approval at http://www.research.ucsf.edu/chr/NewInv/chrNewInv.asp. Information on training, including online training resources, can be found on the CHR website at http://www.research.ucsf.edu/chr/Train/chrTrain.asp.

Under limited circumstances, research involving only unidentifiable or coded private information or specimens is not considered human subjects research (refer to http://www.research.ucsf.edu/chr/Guide/chrExemptApp.asp#NotHuman). This can be determined and certified by the Principal Investigator based on the diagram Determining Whether Human Subjects are Involved in Research When Obtaining Private Information (data) or Biological Specimens, http://www.research.ucsf.edu/chr/guide/HSDecisTree.pdf. If only coded/unidentifiable samples or data will be used in the proposed research, a CHR waiver or self-certification will be required (refer to Exempt Certification and Non-Human Subject Research Application http://www.research.ucsf.edu/chr/guide/chrExemptApp.asp).

Program Contact
Direct questions regarding submission or reporting procedures to Rebecca Cantor (phone: 415.502.5708, email: rebecca.cantor@ucsf.edu).

Selection of Awardees:
Funding decisions are made independently by each funding agency based on several factors – scientific review score, alignment of proposal to funder’s strategic goals, proposal research area of focus, and specifically called out eligibility or other requirements like membership in a center, affiliation with a specific school or relevance to a stated auxiliary topic.

TO APPLY:

STEP 1) Complete the electronic application form
STEP 2) Upload your proposal as a SINGLE PDF that includes all the things listed in numeric order in the instructions below.


INSTRUCTIONS FOR PROPOSAL PDF

Please write your proposal following the instructions listed below and create one single PDF file.

Proposal Length: Maximum 6 pages, including figures and tables, excluding table of contents and literature cited.
Format Requirements: Arial font; 11 pt; minimum 0.5 inch for all margins; no appendices; include page numbers and table of contents.

  1. P.I. Name (no multiple PIs).
  2. Project Title
  3. Proposal - (maximum 6 pages, including figures and tables, excluding literature cited)
  • Aims
  • Background and Significance
  • Preliminary studies
  • Experimental Design and Methods (include time-table)
  • Explain how this pilot project is important for your career goals (e.g., lead to major funding, etc.
  • Mentoring Plan: Describe the plan for oversight of this project by your mentor(s), including the specific role of your primary mentor named in this application. (Not included in the page limit)
  • Literature cited (not included in the page limit)
  • Protection of Human Subjects description (if applicable)
  1. Detailed Budget: $45,000 in direct costs for a one-year period. Please round up to the nearest thousand (i.e. instead of $44,869 list $45,000).
     

Allowable Costs:

Mentored Science Award Program Budget

Allowable

Not Allowable

PI Salary

X

 

Co-Investigator(s) Salary

X

 

Post Doc Salary

X

 

Administrative Support

 

X

Supplies

X

 

Equipment

X

 

Software

X

 

Personal Computers*

X

 

Mailing

X

 

Tuition

X

 

Travel

X

 

Research Staff Support (e.g. RSA; Lab. Technician)

X

 

Patient Care

 

X

Others Expenses**

X

 

* Computers are only allowable when essential to the conduct of the proposed research. If the computer is planned to be used for other projects / responsibilities , we request that the cost of the computer be shared with those other project budgets, in accordance with the amount of use anticipated by each project.
** Refer to the UCSF Charging Practices and Guidelines of allowable Expenses http://controller.ucsf.edu/pam/cas_guidelines.asp

  1. Budget Justification: Clearly and fully justify all costs.
  2. NIH Biosketches for Principal Investigator and Mentor (each 5 page maximum).
  3. Letters of Support: Provide the following two letters of support at the end of your PDF proposal and address them to the RAP Committee.

    Mentor’s Letter of Support - Include a letter of support from your research mentor that includes information outlined below:
  • Specific areas in which mentoring will be provided/mentor’s role in the project
  • Mentor’s background in mentoring
  • How the project fits with the mentor’s research agenda and applicant’s career development
  • The mentor’s working relationship (previous and/or current) with applicant

Additional Letter of Support-- Provide a letter of support from the department chair or other unit head. For all applicants, the department chair/unit head should indicate support for the application with signature. In addition, for postdoctoral investigators, department chairs/unit heads must comment on the independence of the applicant, their status as it pertains to consideration for a faculty appointment, and availability of lab space and other resources for the proposed research and indicate their support for the submission of the application.