Global Cancer Pilot Award

Project Award Amount: Up to $40,000 in direct costs over one year

Description:

Cancer now accounts for more deaths worldwide than HIV/AIDS, tuberculosis, and malaria combined. By 2030, the number of annual global cancer deaths is projected to reach 13.2 million, due to population growth and aging. Nearly 70% of cancer-related deaths will occur in low- and middle-income countries (LMICs). The purpose of these grants is to support innovative projects that address topics related to prevention, screening, diagnosis, and/or treatment of cancer in LMICs.

These pilot awards are intended to support a wide range of research, including basic science, clinical/translational science, implementation science, epidemiology, social science, and behavioral science. Though all types of research will be considered, proposals with a strong, clearly-defined public health impact will be priortized. While applications to develop capacity-building projects are allowable, this mechanism will prioritize the funding of research projects that will lead to future NIH grant proposals or other substantive extramural funding. The project must be a collaboration between a UCSF faculty member or trainee and a named investigator at an academic institution in a LMIC. A letter of support from the collaborating LMIC institution is required with the submission. Residents, Post-Doctoral Fellows, or Clinical Fellows are encouraged to apply with a named UCSF faculty member on the application.

Funding decisions will be based on merit, responsiveness to this call for proposals, feasibility of completing the project in a timely manner, alignment with UCSF HDFCCC Global Cancer Program priorities, and availability of funds. In light of the Global Cancer Program’s aim to foster multi-disciplinary collaboration, proposals that stimulate new collaborations of scientists from diverse fields are strongly encouraged.

Eligibility
Eligibility requirements need to be met as of date of submission; no waivers are allowed.

Who's Eligible:
UCSF Faculty in any series (Ladder Rank, In Residence, Clinical X, Health Science Clinical, Adjunct) at all ranks (Instructors, Assistant, Associate, Full Professors) may apply.  Appointees to the Professional Research Series and Librarian Series may also apply. Residents, Post-Doctoral Fellows, and Clinical Fellows with protected research time are also eligible. If the Primary applicant is a trainee, a UCSF faculty mentor should be named.

Who’s Not Eligible?
Graduate students, and Specialists.

Submission Rules

Criteria for Review/Evaluation of Applications
Projects that are in alignment with the overall priorities of the UCSF HFDCCC Global Cancer Program are encouraged. These priorities include developing or building meaningful collaborations between UCSF and LMIC institutions. Proposals will be evaluated based on the quality of the proposed scientific investigation, the significance of the proposed research for the field of global cancer, the overall public health impact, and the potential of the proposal to lead to future successful NIH grant applications. Pilot projects that involve human subjects will require human research committee approval before funding is released.

TO APPLY:

STEP 1) Complete the electronic application form.  Please note there are several pieces of information that need to be provided directly via the electronic application form (selecting the appropriate grant mechanism, providing demographic information, uploading an abstract, etc.).

Click here to preview an inactive template of the electronic application form.

STEP 2) Upload your proposal as a SINGLE PDF that includes all the things listed in numeric order in the instructions below. 


INSTRUCTIONS FOR PROPOSAL PDF 

Please write your proposal following the instructions listed below and create one single PDF file. Do not include form fields in your PDF document.

Proposal Length: Maximum 6 pages, including figures and tables, excluding table of contents, literature cited and Community Engagement component (if applicable).

Format Requirements: Arial font; 11 pt; minimum 0.5 inch for all margins; no appendices; include page numbers and table of contents.

1. P.I. Name(s) - If funded, PI1 will be the primary contact for the award set up and management. If the proposal has multiple PIs, both PI1 and PI2 need to meet the eligibility criteria listed for this grant mechanism. Only ONE application as PI (PI1 or PI2) is permitted per cycle.

2. Project Title

3. Proposal (maximum 6 pages, including figures and tables, excluding literature cited and Community Engagement component (if applicable).

  • Aims. Do not submit an application that describes an idea that is the same or similar to one used in a previously funded RAP grant. If it is a similar idea, describe how the new proposed research is uniquely different.
  • Feasibility: Describe what steps you are taking to ensure the proposed project can be completed within the one year project period for this grant (approximately 300 word max).
  • Background and Significance
  • Preliminary studies
  • Experimental Design and Methods (include time-table)
  • Explain how this pilot project is important for your career goals (e.g., lead to major funding, etc).

4. Detailed Budget: $40,000 maximum per proposal; and round up to the nearest thousand
    (i.e. instead of $39,869 list $40,000). 
    Use the following form: PHS 398 Form Page 4 "Detailed Budget for the Initial Period": 
    http://grants.nih.gov/grants/funding/phs398/phs398.html
    Add the network recharge rates to your budget.

    Budget Preparation Resources:
    OSR: Develop a Budget 
    Standard Budget Components, including information on personnel costs (salary and benefits)
    NIH: Develop Your Budget

 

Allowable

Not Allowable

PI Salary *

X

 

Co-Investigator(s) Salary

X

 
Network Recharge Rates X  

Post Doc Salary

X

 

Administrative Support

X

 

Supplies

X

 

Equipment

X

 

Software

X

 

Personal Computers

X

 

Mailing

X

 

Tuition

X

 

Travel

X

 

Research Staff Support (e.g. RSA; Lab. Technician)

X

 

Patient Care

X

 

International Subcontracts**

X
 

 

Indirect costs on Subcontracts

   

General Guidelines:
*The NIH base salary cap applies.  PIs are required to list their effort whether it is paid or in kind

PI partial salary support should be well-justified with respect to project activities. Due to their small size, RAP grants are designed for project support and are not intended to provide PI salary support unrelated to the project.  PI salary amounts greater than ~10% of the requested award amount (e.g., $5,000 of a $50K award proposal, not 10% FTE) must be well justified and it should reflect work done by the PI to conduct specific scientific tasks on the project (e.g. data collection, computation) and not merely general supervision of project goals and personnel.

Multiple PIs can decide how to distribute the 10% salary support among themselves (e.g., 5%/5% or 6%/4%). 

  • The 10% limit on salary support is a guideline and includes SALARY & FRINGE BENEFITS.
  • Update: General Automobile and Employee Liability (GAEL) are NOT allowable costs.
  • The award amount is DIRECT COST ONLY.

5. Budget Justification: Clearly and fully justify all costs.
For all personnel, clearly identify any discrepancies between the actual effort (i.e. real percent time) the individual will contribute to the project, versus the amount of salary effort they are requesting.  This is particularly important for personnel/PI's who expect to contribute project effort with little or no salary, such as those whose salary is above the NIH base salary cap.

Recall: PI salary amounts greater than ~10% of the requested award amount must be well justified.

6. NIH Bio-sketch of Principal Investigator(s) and Co-Investigator(s) and UCSF Faculty Mentor(s) (if applicable) (5 page maximum).
Use this version: Biosketch Version F. Include biosketches for all PIs of a multi-PI application, and any other key personnel such as Co-Investigator(s) or UCSF Faculty Mentor(s). In section "D. Additional Information", list the relevant recent past, planned, active, and pending proposals, including percent effort and total direct costs (annual), where possible. Include a brief discussion of any potential overlap with the current proposal.

 7. Letter(s) of support: Provide a letter of support from the department chair or other unit head VIEW SAMPLE.  In addition, for junior investigators, department chairs/unit heads should comment on the independence of the applicant and availability of research space and other resources for the proposed research. Include the letter of support at the end of your PDF proposal and address it to the RAP Committee. If there are multiple (two) PIs, a letter of support is required for both PIs. If PIs are in the same department, the chair can vouch for both PIs in a single letter.  A letter of support from the collaborating LMIC institution is required with the submission.