Marguerita Lightfoot, PhD

Faculty Director
Academic Senate
+1 415 502-1000 ext. 66312

Marguerita Lightfoot, PhD is Professor of Medicine at the UCSF School of Medicine, Chief for the Division of Prevention Science, and Director of the Center for AIDS Prevention Studies (CAPS) and UCSF Prevention Research Center (PRC). She has an established research career conducting community-involved research, receiving awards for my community partnership efforts. She has considerable experience designing and implementing preventive interventions and has developed culturally competent, efficacious HIV interventions for delinquent adolescents, runaway/homeless youth, youth living with HIV, and young MSM, including developing interventions for delivery via technology (e.g., computers, websites, mobile phone, video games). In particular, she developed an efficacious computer-based intervention to reduce the sexual risk behaviors of delinquent youth (published in the American Journal of Public Health), successfully adapted an intervention for youth living with HIV to youth in Uganda (published in Prevention Science), and developed a computer-based intervention implemented in medical settings to reduce the HIV transmission risk behavior of adults living with HIV (published in JAIDS). She is particularly interested in developing cost-effective interventions that are easily translatable with utility in community settings and utilizes new technologies to engage disenfranchised individuals in health promotion activities. She has also conducted psychotherapy with predominately African American and Latino adolescents, adults, and families infected and/or affected by HIV.


The Urgent and Growing Needs of Youths Experiencing Homelessness During the COVID-19 Pandemic.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Auerswald CL, Adams S, Lightfoot M

A Community-Engaged Approach to Creating a Mobile HIV Prevention App for Black Women: Focus Group Study to Determine Preferences via Prototype Demos.

JMIR mHealth and uHealth

Chandler R, Hernandez N, Guillaume D, Grandoit S, Branch-Ellis D, Lightfoot M

Disparities in the PrEP continuum for trans women compared to MSM in San Francisco, California: results from population-based cross-sectional behavioural surveillance studies.

Journal of the International AIDS Society

Wilson EC, Turner CM, Arayasirikul S, Lightfoot M, Scheer S, Raymond HF, Liu A

Psychological Distress, Felt Stigma, and HIV Prevention in a National Probability Sample of Sexual Minority Men.

LGBT health

Krueger EA, Holloway IW, Lightfoot M, Lin A, Hammack PL, Meyer IH

The Architecture of an Internal, Scientific, Presubmission Review Program Designed to Increase the Impact and Success of Grant Proposals and Manuscripts.

Academic medicine : journal of the Association of American Medical Colleges

Johnson MO, Neilands TB, Kegeles SM, Gaffney S, Lightfoot MA

Adaptation of an effective school-based sexual health promotion program for youth in Colombia.

Social science & medicine (1982)

Morales A, Garcia-Montaño E, Barrios-Ortega C, Niebles-Charris J, Garcia-Roncallo P, Abello-Luque D, Gomez-Lugo M, Saavedra DA, Vallejo-Medina P, Espada JP, Lightfoot M, Martínez O

Risk Factors for Substance Use Among Youth Experiencing Homelessness.

Journal of child & adolescent substance abuse

Lightfoot M, Wu N, Hughes S, Desmond K, Tevendale H, Stevens R

Using a Social Network Strategy to Distribute HIV Self-Test Kits to African American and Latino MSM.

Journal of acquired immune deficiency syndromes (1999)

Lightfoot MA, Campbell CK, Moss N, Treves-Kagan S, Agnew E, Kang Dufour MS, Scott H, Sa'id AM, Lippman SA

Strategies to Increase HIV Testing Among MSM: A Synthesis of the Literature.

AIDS and behavior

Campbell CK, Lippman SA, Moss N, Lightfoot M

Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.

PloS one

Morales A, Espada JP, Orgilés M, Escribano S, Johnson BT, Lightfoot M

"Like finding a unicorn": Healthcare preferences among lesbian, gay, and bisexual people in the United States.

Social science & medicine (1982)

Martos AJ, Wilson PA, Gordon AR, Lightfoot M, Meyer IH

Effectiveness of School-Based Teen Pregnancy Prevention Programs in the USA: a Systematic Review and Meta-Analysis.

Prevention science : the official journal of the Society for Prevention Research

Marseille E, Mirzazadeh A, Biggs MA, P Miller A, Horvath H, Lightfoot M, Malekinejad M, Kahn JG

The Use of Mobile Health Applications Among Youth and Young Adults Living with HIV: Focus Group Findings.

AIDS patient care and STDs

Saberi P, Siedle-Khan R, Sheon N, Lightfoot M

Contextual influence of Taiwanese adolescents' sexual attitudes and behavioral intent.

Nursing & health sciences

Chen AC, Neilands TB, Chan SM, Lightfoot M

Compliance to Cell Phone-Based EMA Among Latino Youth in Outpatient Treatment.

Journal of ethnicity in substance abuse

Comulada WS, Lightfoot M, Swendeman D, Grella C, Wu N

Adolescents in wartime US military families: a developmental perspective on challenges and resources.

Clinical child and family psychology review

Milburn NG, Lightfoot M

Text-messaging-enhanced HIV intervention for African American adolescents: a feasibility study.

The Journal of the Association of Nurses in AIDS Care : JANAC

Cornelius JB, Dmochowski J, Boyer C, St Lawrence J, Lightfoot M, Moore M

HIV prevention for adolescents: where do we go from here?

The American psychologist

Lightfoot M

The intersection of youth, technology, and new media with sexual health: moving the research agenda forward.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Allison S, Bauermeister JA, Bull S, Lightfoot M, Mustanski B, Shegog R, Levine D

Vocational training with HIV prevention for Ugandan youth.

AIDS and behavior

Rotheram-Borus MJ, Lightfoot M, Kasirye R, Desmond K

Hopelessness and sexual risk behavior among adolescent African American males in a low-income urban community.

American journal of men's health

Kagan S, Deardorff J, McCright J, Lightfoot M, Lahiff M, Lippman SA

Finding shelter: two-year housing trajectories among homeless youth.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Tevendale HD, Comulada WS, Lightfoot MA

A family intervention to reduce sexual risk behavior, substance use, and delinquency among newly homeless youth.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Milburn NG, Iribarren FJ, Rice E, Lightfoot M, Solorio R, Rotheram-Borus MJ, Desmond K, Lee A, Alexander K, Maresca K, Eastmen K, Arnold EM, Duan N

Psychiatric risk factors for HIV disease progression: the role of inconsistent patterns of antiretroviral therapy utilization.

Journal of acquired immune deficiency syndromes (1999)

Carrico AW, Riley ED, Johnson MO, Charlebois ED, Neilands TB, Remien RH, Lightfoot MA, Steward WT, Weinhardt LS, Kelly JA, Rotheram-Borus MJ, Morin SF, Chesney MA

Development and pretesting multimedia HIV-prevention text messages for mobile cell phone delivery.

The Journal of the Association of Nurses in AIDS Care : JANAC

Cornelius JB, Cato M, Lawrence JS, Boyer CB, Lightfoot M

Protective factors associated with fewer multiple problem behaviors among homeless/runaway youth.

Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53

Lightfoot M, Stein JA, Tevendale H, Preston K

Efficacy of brief interventions in clinical care settings for persons living with HIV.

Journal of acquired immune deficiency syndromes (1999)

Lightfoot M, Rotheram-Borus MJ, Comulada WS, Reddy VS, Duan N


Journal of community psychology

Milburn N, Liang LJ, Lee SJ, Rotheram-Borus MJ, Rosenthal D, Mallett S, Lightfoot M, Lester P

Effects of behavioral intervention on substance use among people living with HIV: the Healthy Living Project randomized controlled study.

Addiction (Abingdon, England)

Wong FL, Rotheram-Borus MJ, Lightfoot M, Pequegnat W, Comulada WS, Cumberland W, Weinhardt LS, Remien RH, Chesney M, Johnson M

Affect regulation, stimulant use, and viral load among HIV-positive persons on anti-retroviral therapy.

Psychosomatic medicine

Carrico AW, Johnson MO, Moskowitz JT, Neilands TB, Morin SF, Charlebois ED, Steward WT, Remien RH, Wong FL, Rotheram-Borus MJ, Lightfoot MA, Chesney MA

Efficacy of a culturally adapted intervention for youth living with HIV in Uganda.

Prevention science : the official journal of the Society for Prevention Research

Lightfoot MA, Kasirye R, Comulada WS, Rotheram-Borus MJ

It's not just what you say: relationships of HIV dislosure and risk reduction among MSM in the post-HAART era.

AIDS care

Klitzman R, Exner T, Correale J, Kirshenbaum SB, Remien R, Ehrhardt AA, Lightfoot M, Catz SL, Weinhardt LS, Johnson MO, Morin SF, Rotheram-Borus MJ, Kelly JA, Charlebois E

Self-monitoring of behaviour as a risk reduction strategy for persons living with HIV.

AIDS care

Lightfoot M, Rotheram-Borus MJ, Comulada S, Gundersen G, Reddy V

An HIV-preventive intervention for youth living with HIV.

Behavior modification

Lightfoot M, Rotheram-Borus MJ, Tevendale H

Depressive symptomatology among HIV-positive women in the era of HAART: a stress and coping model.

American journal of community psychology

Remien RH, Exner T, Kertzner RM, Ehrhardt AA, Rotheram-Borus MJ, Johnson MO, Weinhardt LS, Kittel LE, Goldstein RB, Pinto RM, Morin SF, Chesney MA, Lightfoot M, Gore-Felton C, Dodge B, Kelly JA

Who benefited from an efficacious intervention for youth living with HIV: a moderator analysis.

AIDS and behavior

Lightfoot M, Tevendale H, Comulada WS, Rotheram-Borus MJ

Computerized HIV preventive intervention for adolescents: indications of efficacy.

American journal of public health

Lightfoot M, Comulada WS, Stover G

Predicting HIV transmission risk among HIV-infected men who have sex with men: findings from the healthy living project.

Journal of acquired immune deficiency syndromes (1999)

Morin SF, Steward WT, Charlebois ED, Remien RH, Pinkerton SD, Johnson MO, Rotheram-Borus MJ, Lightfoot M, Goldstein RB, Kittel L, Samimy-Muzaffar F, Weinhardt L, Kelly JA, Chesney MA

Psychological distress, substance use, and adjustment among parents living with HIV.

The Journal of the American Board of Family Practice

Goldstein RB, Johnson MO, Rotheram-Borus MJ, Kirshenbaum SB, Pinto RM, Kittel L, Pequegnat W, Mickalian JD, Weinhardt LS, Kelly JA, Lightfoot M

Health and health care among male-to-female transgender persons who are HIV positive.

American journal of public health

Melendez RM, Exner TA, Ehrhardt AA, Dodge B, Remien RH, Rotheram-Borus MJ, Lightfoot M, Hong D

Insurance coverage, usual source of care, and receipt of clinically indicated care for comorbid conditions among adults living with human immunodeficiency virus.

Medical care

Goldstein RB, Rotheram-Borus MJ, Johnson MO, Weinhardt LS, Remien RH, Lightfoot M, Catz SL, Gore-Felton C, Kirshenbaum S, Morin SF

Prevention for HIV-seropositive persons: successive approximation toward a new identity.

Behavior modification

Lightfoot M, Rotheram-Borus MJ, Milburn NG, Swendeman D

Risk behaviors of youth living with HIV: pre- and post-HAART.

American journal of health behavior

Lightfoot M, Swendeman D, Rotheram-Borus MJ, Comulada WS, Weiss R

Predictors of substance use frequency and reductions in seriousness of use among persons living with HIV.

Drug and alcohol dependence

Lightfoot M, Rogers T, Goldstein R, Rotheram-Borus MJ, May S, Kirshenbaum S, Weinhardt L, Zadoretzky C, Kittel L, Johnson M, Gore-Felton C, Morin SF

Perceived adverse effects of antiretroviral therapy.

Journal of pain and symptom management

Johnson MO, Charlebois E, Morin SF, Catz SL, Goldstein RB, Remien RH, Rotheram-Borus MJ, Mickalian JD, Kittel L, Samimy-Muzaffar F, Lightfoot MA, Gore-Felton C, Chesney A

The Healthy Living Project: an individually tailored, multidimensional intervention for HIV-infected persons.

AIDS education and prevention : official publication of the International Society for AIDS Education

Gore-Felton C, Rotheram-Borus MJ, Weinhardt LS, Kelly JA, Lightfoot M, Kirshenbaum SB, Johnson MO, Chesney MA, Catz SL, Ehrhardt AA, Remien RH, Morin SF

The influence of partner type and risk status on the sexual behavior of young men who have sex with men living with HIV/AIDS.

Journal of acquired immune deficiency syndromes (1999)

Lightfoot M, Song J, Rotheram-Borus MJ, Newman P

Prevention for substance-using HIV-positive young people: telephone and in-person delivery.

Journal of acquired immune deficiency syndromes (1999)

Rotheram-Borus MJ, Swendeman D, Comulada WS, Weiss RE, Lee M, Lightfoot M

HIV transmission risk behavior among men and women living with HIV in 4 cities in the United States.

Journal of acquired immune deficiency syndromes (1999)

Weinhardt LS, Kelly JA, Brondino MJ, Rotheram-Borus MJ, Kirshenbaum SB, Chesney MA, Remien RH, Morin SF, Lightfoot M, Ehrhardt AA, Johnson MO, Catz SL, Pinkerton SD, Benotsch EG, Hong D, Gore-Felton C

Intricacies and inter-relationships between HIV disclosure and HAART: a qualitative study.

AIDS care

Klitzman RL, Kirshenbaum SB, Dodge B, Remien RH, Ehrhardt AA, Johnson MO, Kittel LE, Daya S, Morin SF, Kelly J, Lightfoot M, Rotheram-Borus MJ

Theory-guided, empirically supported avenues for intervention on HIV medication nonadherence: findings from the Healthy Living Project.

AIDS patient care and STDs

Johnson MO, Catz SL, Remien RH, Rotheram-Borus MJ, Morin SF, Charlebois E, Gore-Felton C, Goldsten RB, Wolfe H, Lightfoot M, Chesney MA

Four-year behavioral outcomes of an intervention for parents living with HIV and their adolescent children.

AIDS (London, England)

Rotheram-Borus MJ, Lee M, Leonard N, Lin YY, Franzke L, Turner E, Lightfoot M, Gwadz M

Efficacy of a preventive intervention for youths living with HIV.

American journal of public health

Rotheram-Borus MJ, Lee MB, Murphy DA, Futterman D, Duan N, Birnbaum JM, Lightfoot M

Negotiating behavior change with HIV-positive adolescent girls.

AIDS patient care and STDs

Lightfoot M, Rotheram-Borus MJ