Pilot Award for Prevention and Treatment of Opioid Use Disorders

Project Award Amount $40,000 (Spring Cycle Only)

Description

This funding opportunity is intended to support research projects focused on prevention and treatment of opioid use disorders. We are particularly interested in projects that will generate preliminary data needed to develop clinical trials or population-based community interventions. Projects should be relevant to these broad areas related to opioids: pain management, standard of care and opioid prescribing patterns; and improving prevention or treatment of opioid misuse and addiction.

Applications in any aspect of clinical research will be considered. Examples include:

  • Implementation strategies for evidence-based approaches in multiple settings including primary and emergency care, the criminal justice system, and other community settings, and in communities highly affected by the opioid crisis;
  • Populations that may be at-risk which include older adolescents and young adults (ages 16-30) which is a group at highest risk for opioid initiation, misuse, OUD and overdose fatality; individuals born with Neonatal Abstinence Syndrome (NAS)/Neonatal Opioid Withdrawal Syndrome (NOWS); homeless populations; and those with co-occurring health conditions including other substance-abuse disorders, mood and anxiety disorders
  • Evidence-based approaches that can be integrated or embedded into health care systems.

Each pilot project will have a maximum budget of $40,000. Pilot projects are for one year and are not renewable. A progress report is required at the end of the funding period, identifying resulting publications and subsequent funding obtained to support the expanded/extended projects. Any resulting publication must directly acknowledge the funding agency.

Eligibility

Eligibility requirement need to be met as of date of submission, no waivers will be accepted.

Who's Eligible:
UCSF Faculty in any series (Ladder Rank, In Residence, Clinical X, Health Science Clinical, and Adjunct) in all ranks (Instructors, Assistant, Associate, Full Professors) and Appointees to the Professional Research Series and to the Librarian Series may apply. Fellows (unless not allowed by fellowship funders) and Postdocs are eligible.

Who's Not Eligible:
Residents and Specialists.

Criteria for Review/Evaluation of Applications
Proposals will be evaluated based on the quality of the proposed scientific investigation, the significance of the proposed research for the field of opioid use disorders research, the potential of the proposal to lead to future successful NIH grant applications, and the quality and promise of the applicant and the research team.

Pilot projects that involve human subjects will require human research committee approval and NIH Prior Approval review before funding is released.

Selection of Awardees
Funding decisions are made independently by each funding agency based on several factors – scientific review score, alignment of proposal to funder’s strategic goals, proposal research area of focus, and specifically called out eligibility and priority areas.

TO APPLY:

STEP 1) Complete the electronic application form
STEP 2) Upload your proposal as a SINGLE PDF that includes all the things listed in numeric order in the instructions below.


INSTRUCTIONS FOR PROPOSAL PDF

Please write your proposal following the instructions listed below and create one single PDF file. Do not include form fields in your PDF document.

Proposal Length: Maximum 6 pages, including figures and tables, excluding table of contents, literature cited and community engagement, if applicable.
Format Requirements: Arial font; 11 pt; minimum 0.5 inch for all margins; no appendices; include page numbers and table of contents.

Resubmissions
Definition: Same research topic with an amended application or research plan rather than a new research topic and new research plan.
Requirements: Please use up to one extra page to introduce your revised proposal, addressing the issues raised in the review, and any additional changes to your proposal. A new letter from the Chair is not required if the resubmission is within 2 cycles (one skipped cycle max). You will include the old letter and state your resubmission is within 2 cycles and new letter is not required. Make sure the new changes are highlighted in bold or italic font so the reviewers can easily see where and how the proposal has changed. Do not use track changes.

1. P.I. Name(s) - Optionally, you may apply with two PIs. If funded, PI1 will be the primary contact for the award set up and management. If the proposal has multiple PIs, both PI1 and PI2 need to meet the eligibility criteria listed for this grant mechanism. Only ONE application as PI (PI1 or PI2) is permitted per cycle.

2. Project Title

3. Proposal (maximum 6 pages, including figures and tables, excluding literature cited)

  • Aims. Do not submit an application that describes an idea that is the same or similar to one used in a previously funded RAP grant. If it is a similar idea, describe how the new proposed research is uniquely different.
  • Feasibility: Describe what steps you are taking to ensure the proposed project can be completed within the one year project period for this grant (approximately 300 word max).
  • Background and Significance
  • Preliminary studies
  • Research Design and Methods (include time-table)
  • Explain how this pilot project is important for your career goals (e.g., lead to major funding, etc.)
  • Mentoring Plan: (required for fellows and junior faculty)
    Please describe the plan for oversight of this project by your mentor(s), including the specific role of your primary mentor named in this application.
  • Community Engagement Component (optional) describe a community engagement component for your research proposal (300 words max). Projects that engage in community partnership practices are characterized by increasing level of community involvement, impact, trust and communication flow (from stages of involve, collaborate and shared leadership). For examples of excellence in community partnerships, please visit: https://partnerships.ucsf.edu/excellence-partnership-awardees#2014. Community broadly includes local, state, national and international stakeholders. Stakeholders include researchers, health systems, government, policy makers, community based organizations, community residents and patients. For clarification, questions and consultations, please contact either [email protected] or [email protected]

  • Literature cited (not included in page limit)

4. Detailed Budget $40,000 maximum per proposal and please round up to the nearest thousand (i.e. instead of $39,869 list $40,000).
Use the following form: PHS 398 Form Page 4, "Detailed Budget for the Initial Period": http://grants.nih.gov/grants/funding/phs398/phs398.html
Add the network recharge rates to your budget.

 

Allowable

Not Allowable

PI Salary *

X

 

Co-Investigator(s) Salary

X

 

Post Doc Salary

X

 

Administrative Support

 

X

Supplies

X

 

Equipment

 

X

Software

 

X

Personal Computers

 

X

Mailing

 

X

Tuition

 

X

Travel

 

X

Research Staff Support (e.g. SRA; Lab. Technician)

X

 

Patient Care

X

X

International Subcontracts

 

X

Indirect costs on subcontracts

 

X

*NIH base salary cap. Fully justify all requests. Generally PI partial salary support should not exceed 10% of the budget, anything over 10% must be well justified. Multiple PIs can decide how to distribute that 10% salary support among them (e.g., 5%/5% or 6%/4%).

5. Budget Justification: Clearly and fully justify all costs.

6. NIH Bio-sketch of Principal Investigator(s) and Co-Investigator(s) and UCSF Faculty Mentor(s) (if applicable) (5 page maximum):
Use this version: Biosketch Version E. Include biosketches for all PIs of a multi-PI application, and any other key personnel such as Co-Investigator(s) or UCSF Faculty Mentor(s). In section "D. Additional Information", list the relevant recent past, planned, active, and pending proposals, including percent effort and total direct costs (annual), where possible. Include a brief discussion of any potential overlap with the current proposal.

7. Letter(s) of support: Provide a letter of support from the department chair or other unit head. In addition, for junior investigators, department chairs/unit heads should comment on the independence of the applicant and availability of research space and other resources for the proposed research. Include the letter of support at the end of your PDF proposal and address it to the RAP Committee. If there are multiple (two) PIs, a letter of support is required for both PIs. If PIs are in the same department, the chair can vouch for both PIs in a single letter.